Title
Crystal structure of Trypanosoma cruzi histone deacetylase DAC2 complexed with Quisinostat
Method
X-RAY DIFFRACTION; 1.75 Å
Target Sequence
Sequence
Target Structure
Chain A
Quaternary State
Monomer
Oligo Target Structure
Biounit 1

Submitted model details

1
467
Structure (11 - 425, 415 res.)
Phyre2, model-1 (37 - 446)
RoseTTAFold, model-1 (1 - 467)
RoseTTAFold, model-2 (1 - 467)
RoseTTAFold, model-3 (1 - 467)
RoseTTAFold, model-4 (1 - 467)
RoseTTAFold, model-5 (1 - 467)
SWISS-MODEL, model-1 (14 - 447)
SWISS-MODEL, model-2 (8 - 370)
SWISS-MODEL, model-3 (80 - 444)
RaptorX, model-1 (1 - 467)
IntFOLD3-TS, model-1 (1 - 467)
IntFOLD3-TS, model-2 (1 - 467)
IntFOLD3-TS, model-3 (1 - 467)
IntFOLD3-TS, model-4 (1 - 467)
IntFOLD3-TS, model-5 (1 - 467)
NaiveBLAST, model-1 (76 - 417)
IntFOLD4-TS, model-1 (1 - 467)
IntFOLD4-TS, model-2 (1 - 467)
IntFOLD4-TS, model-3 (1 - 467)
IntFOLD4-TS, model-4 (1 - 467)
IntFOLD4-TS, model-5 (1 - 467)
PRIMO, model-1 (27 - 445)
PRIMO_BST_CL, model-1 (27 - 445)
IntFOLD6-TS, model-1 (1 - 467)
IntFOLD6-TS, model-2 (1 - 467)
IntFOLD6-TS, model-3 (1 - 467)
IntFOLD6-TS, model-4 (1 - 467)
IntFOLD6-TS, model-5 (1 - 467)
pureAF2_orig, model-1 (1 - 467)
pureAF2_notemp, model-1 (1 - 467)
ZlxFold, model-1 (1 - 467)
Naive AlphaFoldDB 90, model-1 (2 - 459)
PaFold, model-1 (1 - 467)
HeliXonAI, model-1 (1 - 467)
PaFold_v2, model-1 (1 - 467)
RocketX, model-1 (1 - 467)
RocketX, model-2 (1 - 467)
RocketX, model-3 (1 - 467)
RocketX, model-4 (1 - 467)
RocketX, model-5 (1 - 467)
RocketX, model-6 (1 - 467)
BestSingleStructuralTemplate, model-1 (1 - 467)

Colors: Query Sequence | Target Structure Coordinates | Model #1 Coordinates

3D Prediction

Target Structure

Server Evaluations

Server Name
Predictions Resp. time
(hh:mm:ss)
From To Cov. (%) lDDT lDDT Cα Avg. lDDT-BS Avg. lDDT-BS details Model Conf. lDDT QS-score Oligo details QS-score Best Match lDDT Oligo MM-align TM-score MM-align RMSD QScore CAD-Score GDT_HA RMSD GDC Model Conf. MaxSub TM-score