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CAMEO | CAMEO Tech Corner

Latest Developments for CAMEO

Document Index
Progress in the 3D structure prediction category
Progress in the ligand binding site residue prediction category
General News

We are very grateful for comments and suggestions, bug reports etc. and encourage discussions about CAMEO. Here is a current short list of items which are either in progress or planned for the near future.

Protein Structure Modeling category

In Progress

  1. Improve visualisation of aggregated scores

Planned

  1. Include more scores - model confidence(next), TMScore, MaxSub, physical plausability
  2. Improve navigation - include per server view of week data
  3. Setup weekly summaries for individual server groups
  4. Setup warning emails if after two days no models have been received

Ligand Binding Site Residue Prediction category (currently only on beta site)

In Progress

  1. Activate Script to allow CASP style formatted predictions to be accepted. For new format please refer here.
  2. Improve Visualisation of aggregated scores

Planned

  1. Extend assessment to compound category
  2. Include more plots for the prediction detail pages

CAMEO Overall Project Status

  • March 2012: Added two public (M4T and Robetta) and one development server.
  • Feb 2012: Added new private server.
  • Feb 2012: Improved visualisation of coverage scores, added ldt plot and changed entry plot for 3D structure prediciton category to show coverage vs Accuracy (GDT_HA) and the response time is illustrated with the different radii of the individual data points in this plot(still on beta site).
  • Feb 2012: Improve Visualisation of aggregated scores
  • Jan 2012: Added new development server.
  • Jan 2012: First support of ligand binding site residue preditions assessment (beta site )
  • October 2011: CAMEO went "public", now based on the weekly prerelease of protein sequences by the PDB to be submitted every Friday, 5 days ahead of the PDB release.
  • December 2010: Public Announcement of CAMEO at CASP9
  • October 2010: CAMEO starts operating in "beta" testing mode with a small number of prediction servers in postdiction mode by extracting the sequences from the latest PDB release.
  • June 2010: The "Working group on theoretical model validation" decided during its kick-off meeting at Rutgers to establish a continuous evaluation service linked to Protein Model Portal