CAMEO | FAQ

Does CAMEO build models for users?
No. CAMEO is not a meta-server and will not answer user requests. Its sole purpose is to continuously evaluate the accuracy of prediction servers based on known experimental structures released by the PDB.

Which servers will be evaluated?
CAMEO will only evaluate servers with the consent of the author. We invite all server developers to register their services to CAMEO. Please use the following on-line registration form [REGISTER], or contact us directly by email if your service does not fit within these categories.
See our complete list of registered servers.

Is all CAMEO data public?
Authors of a prediction server can decide if their evaluation data is public or only accessible privately. Services initially registered as "private" (e.g. during the development phase) can later be changed to "public" (e.g. for publication purposes).

Can I suggest a new score / evaluation method?
Yes, of course. CAMEO is a community service, and we don’t expect that our initial set of scores will be perfect. In fact, we know it is not. If you would like to see a different evaluation score applied, please let us know!

Which prediction methods are covered by CAMEO?
In the current release, CAMEO addresses the evaluation of services for protein structure prediction . In the following months, we plan to open CAMEO for assessment of "Model Quality Estimation Tools", "Ligand Binding predictions", "Secondary Structure Prediction" and "Solvent Accessible Surface", etc following the demand by the community.

Can I submit several models for a target protein in CAMEO?
No. CAMEO will include only one prediction per server for each target sequence in the overall score. If you server can be tuned with different parameters (e.g. for highest coverage or for highest accuracy), you will need to register two servers with different parameters - each submitting one model. Please use the following on-line registration form [REGISTER], or contact us directly by email (help-cameo@proteinmodelportal.org) if you have any questions.

How does CAMEO relate to CASP?
In CASP, expert groups aim to predict structures of 50-100 target proteins for which the coordinates will not be published during the prediction window (3 weeks). The results are assessed blindly by independent assessors. In CAMEO, automated prediction servers are continuously benchmarked using thousands of newly released structures from the PDB on a weekly basis. The assessment is fully automated.

The results of CAMEO will be presented at the bi-annual CASP meeting.
Some prediction categories in CASP have matured to a point where automated assessment is possible and manual assessment no longer required (e.g. "Secondary Structure Prediction", etc.). These categories are no longer part of CASP and will only be assessed by CAMEO.

How do I register my modeling server with CAMEO?
In the modeling category each server will submit a single model, so if your server normally delivers one model for highest coverage and one for best quality you would need to register two servers each submitting one model.
Please use the following on-line registration form [REGISTER], or contact us directly by email if your service does not fit within these categories.